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 October 2016

 Volume 2 Issue 10

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Review article

Immunotherapy and Gastric Cancer

Timothy Allen* MD, Ph.D, Giridhar M.N.V , MD, MBA, Ghazaleh Shoja E Razavi MD

Gastric Cancer (GC) is the fourth common cancer worldwide though it has a low incidence in the United States (US). It has a geographical distribution affecting mainly the underprivileged developing countries much more than the affluent developed ones. It is an aggressive disease with high mortality rate. Modest breakthroughs in the treatment of GC occurred in the last couple of decades and it was restricted to chemotherapy and surgical techniques. The development of gastric cancer is a complex, multistep process, which involves multiple genetic and epigenetic alterations.                                          

 

                                                                                                                                                                     Download PDF Full text

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Review article

Immunotherapy and Ovarian Cancer

Timothy Allen* MD, Ph.D, Giridhar M.N.V , MD, MBA, Ghazaleh Shoja E Razavi MD

Ovarian cancer is one of the leading causes of death and poses a significant health challenge worldwide. The standard therapy for ovarian cancer involving use of surgery and platinum chemotherapy had led to recurrence among majority of patients. Recent improvement in the understanding of the etiology and molecular characteritics of ovarian cancer has paved the way for exploring the utility of immunotherapy for ovarian cancer. Currently, Avastin (Bevacizumab) is the only US FDA approved immunotherapy to be used in combination with chemotherapy among women who have advanced ovarian cancer.                                         

                                                                                                                                                                     Download PDF Full text

 

 

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