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 February 2016

Volume 2  Issue 2

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Case report
A Rare Tumoral Combination, Renal Cell Carcinoma, Breast Carcinoma and Non- Hodgkin Lymphoma and Review of the Literature

Şebnem İzmir Güner, Didem Karacetin*, Ekrem Güner M.Teoman Yanmaz, Mahmut Yüksel

Multiple consecutive cancers involving different organs in a female individual are presented. Here in, we present a rare case of primary left renal cell carcinoma (RCC), in which two different malignancies of left cervical lymph node and left breast were occurred consecutively. We present the case of a 84-year-old female with three primary malignant neoplasms detected synchronously. She was admitted to our clinic with left neck upper mass.The result of the left cervical lymph node biopsy revealed diffuse B large cell lymphoma, the result of the left breast biopsy revealed well differantiated invasive ductal carcinoma and the result of the kidney’s noduler biopsy was clear cell carcinoma respectively.
                                              

                                                                                                                                                                     Download PDF Full text

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Research article
Second Primary Lung Cancer: A Current Problem in Long-Survivor Cancer Patients

Felice Mucilli*, Pierpaolo Camplese, Giuseppe Cipollone, Decio Di Nuzzo, Massimo Ippoliti, Luigi Guetti, Marco Prioletta, Mirko Barone, Antonia Rizzuto, Rosario Sacco

Lung may be the site of synchronous or metachronous second primary malignancies (SPM) with an incidence between 0.8 and 14.5% of cases. Synchronous or metachronous SPM present, however, diagnostic and therapeutic challenges. The authors report their experience in the treatment of second primary lung tumors.A retrospective study from 2008 to 2014 was conducted in patients with synchronous or metachronous second primary lung cancer.
                                              

                                                                                                                                                                     Download PDF Full text

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Review article
Novel Approaches in Treatment of Adult AML

Timothy Allen, MD, Ph.D., Ghazaleh Shoja E Razavi* MD

Acute myeloid leukemia (AML) is cancer of the blood cells. This cancer specifically affects red blood cells, platelet forming cells and other white blood cells in the body; its incidence is very low in the United States with less than 3% of cancer diagnoses being for AML. Traditionally, this disease would be treated with chemotherapy or radiation therapy. Immunotherapy is a new way to fight this cancer. This therapy stimulates one’s own immune system to fight the malignant tumor. In this paper, we discuss the causes, epidemiology, and potential immunotherapeutic techniques to fight AML.
                                              

                                                                                                                                                                     Download PDF Full text

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Review article
Novel Targets and Breast Cancer Treatment

Timothy Allen, MD, Ph.D., Ghazaleh Shoja E Razavi* MD

Breast cancer is considered as second most common cancer in women, after skin cancer. One out of every 8 woman in the United States is predisposed to develop breast cancer. It is usually caused by genetic mutations, using certain medication and few even hereditary disorders. Surgery, radiation therapy and chemotherapy are the traditional and mainstay of treatment of breast cancer. However, novel therapies such as targeted therapy have been subject to serious consideration. Targeted therapy mainly focuses on the molecular pathways responsible in process of carcinogenesis, tumor promotion and metastasis. In this paper, we discuss the causes, epidemiology, and potential targeted therapies techniques to treat breast cancer.
                                              

                                                                                                                                                                     Download PDF Full text

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Review article
Therapeutic Approach to Chordomas

Timothy Allen, MD, Ph.D., Ghazaleh Shoja E Razavi* MD

Chordomas are neoplasms that come from the notochord’s cellular remnants. Immunotherapy is a cancer treatment alternative to chemotherapy and radiation therapy. Its goal is to use a patient’s own immune system to fight the tumor. The immune system can be stimulated by exposing synthetic immune molecules into a subject’s system. In this paper, we discuss the potential causes of chordomas, the pathophysiology of the disease, and potential ways to cure the disease using different immunotherapy techniques.
                                              

                                                                                                                                                                     Download PDF Full text

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