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 December 2015

 Volume 1  Issue 6


Research Article
Do Cancer Survivors Live Longer When In A Long-Term-Care Facility? -Possibility of Harmless Cancer In Oldest Old

Kazue Takayanagi, MD, Ph.D*, Yoshikuni Sato, MD, Ph.D

We had an infant patient with advanced neuroblastoma who was reported by several pediatric surgeons with spontaneous remission. We also had a patient with advanced gastric cancer who underwent“Laughter therapy”inducing radical remission. There are many reports on cancer patients from the medical provider side, however, there are few reports available from long-term-care facilities. This report addressed oldest old cancer survivors from the perspective of long- termcare facilities. Furthermore, I had reported our experience on harmless cancer and advanced cancer that did not manifest any symptoms.                                                   

                                                                                                                                 Download PDF Full text


Mini Review
Emerging Approach to Cancer Immunoprevention

Corocleanu Manole MD PhD*

Recent identification of stemness pathways in embryonal stem cells (ES) as well putative cancer stem cells (CSCs) provides novel opportunity toward immunologic approaches targeting of pathways associated with stemness. Also, human full-term placenta has been reported to contain a population of broadly multipotent stem cells. A single transcription factor Oct4 is sufficient to convert nonembryonic-derived trophoblast stem cells cells into pluripotent stem cells i.e. placenta embryonic-like stem cells). As the above types of cell undergo deprogramming to a proliferative stem cell state as result of complex signals in the microenvironment, including oxygen availability the transient expression of hypoxia-regulated Oct4 protein is sufficient to induce stem cell dedifferentiation.                                                   

                                                                                                                                                                     Download PDF Full text

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